Web17 Mar 2024 · Secondary analyses. As we found a potential causal association between FI and erythrocytosis, we undertook univariable MR to investigate the association between FI and HbA1c followed by multivariable MR adjusted for FG, T2D or Hb. Adjustment for FG and T2D was not undertaken in combination due to concerns about collinearity . Adjustment … Web3 Jun 2024 · Expert opinion: PAH-CHD is a wide spectrum of conditions, of which ES is the archetype. The size and location of the shunt, the degree of adaptation of the right ventricle to the increased afterload and other compensatory mechanisms, such as secondary erythrocytosis, define the clinical presentation and natural history of these patients.
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