Mdmx antibody
WebProduct information "Anti-HdmX/MDM4" Protein function: Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. … WebOur MDMX Antibodies can be used in a variety of model species: Human, Monkey, Mouse, Rat. Use the list below to choose the MDMX Antibody which is most appropriate for …
Mdmx antibody
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WebAnti-MDMX/MDM4 antibody [BL-3-2F2] (ab243859) Research with confidence – consistent and reproducible results with every batch Long-term and scalable supply – powered by … WebProtein Recombinant Human MDMX/MDM4 protein (ab167947) Primary Anti-GAS41 antibody (ab205018) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) View more associated products Overview Product name Anti-MDMX/MDM4 antibody [BL-3-2F2] See all MDMX/MDM4 primary antibodies Description Rabbit monoclonal [BL-3-2F2] to …
WebMonoclonal Anti-MDMX antibody is suitable for use in immunocytochemistry, immunoprecipitation, immunoblot (approx. 80 kDa), microarray, and ELISA. The product may also be used for western blot and for assessing ectopic expression of MDMX (using a conc. of 1-2 μg/mL in total cell extract of HEK 293T cells transfected with human MDMX). WebMDMX/MDM4 was immunoprecipitated from Jurkat (human T cell leukemia cell line from peripheral blood) whole cell lysate (1 mg per IP reaction; 20% of IP loaded) using …
WebAnti-Mdmx Antibody, clone 8C6 is a Mouse Monoclonal Antibody for detection of Mdmx also known as MDM4-related protein 1, Mdm2-like p53-binding protein & has been validated in WB, IP, ICC, IHC, FC. Anti-Mdmx Antibody, clone 8C6 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. SDS … WebMdmx is a Mdm2-related protein that like Mdm2 has been shown to bind to and inhibit p53, although not as well as Mdm2. This interaction with p53 occurs via a binding domain …
Web29 mrt. 2012 · Mdmx protein antibody; MGC132766 antibody; Mouse double minute 4 homolog antibody; Mouse double minute 4 human homolog of p53 binding protein …
WebMDMX is a p53-binding protein with significant sequence homology to MDM2 ( 2 , 3 ). Unlike MDM2, MDMX does not have intrinsic E3 ligase activity and does not promote p53 degradation. However, MDMX binds to MDM2 through C-terminal RING domain interaction ( 4 , 5 ) and stimulates the ability of MDM2 to ubiquitinate and degrade p53 ( 6 , 7 ). clean a shark vacuumWebMDMX Protein (1) Recombinant MDMX proteins are expressed by E. coli with fusion tags as N-His. MDMX Antibody (2) MDMX antibodies are validated with different applications, which are WB, ELISA. MDMX cDNA Clone (15) MDMX cDNA clones are full length sequence confirmed and expression validated. There are 13 kinds of tags for each … down to earth organic foodWeb5 jul. 2011 · Expression of Mdmx, Mdm2, or p53 in day-9.5 embryos. (A) Sections from indicated genotype embryos were stained with antibodies against MDMX and p53, respectively. (B) Sections from Mdmx C462A/C462A homozygous or wild-type embryos were stained with anti-MDM2, Bax, or p21 antibodies. The homozygous (HOMO) or wild … down to earth organicsWebRecombinant Human MDMX/MDM4 protein ( ab114467) can be used as a positive control in WB. This antibody gave a positive signal in the following nuclear cell extract: HeLa. This … down to earth opalsWebThe MDM2 protein is the primary regulator of p53 protein stability. MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations … down to earth oregonWeb29 okt. 2024 · The Murine Double Minute 2–Murine Double Minute X (MDM2–MDMX) heterodimer is well known as one of the major negative regulators of the tumor suppressor p53, but the p53-independent functions of MDM2 and MDMX are not as well studied. down to earth organic and naturalWebMDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2. The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas. ARF interacts with MDMX to sequester MDMX within the nucleolus. down to earth organic ghee