WebCircRNA ZNF609 Knockdown Represses the Development of Non-Small Cell Lung Cancer via miR-623/FOXM1 Axis Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled. WebJan 31, 2024 · Objective . The aim of the present study was to investigate the effect of forkhead box M1 (FOXM1) to paclitaxel resistance in cervical cancer cells, to determine the underlying mechanism, and to identify novel targets for the treatment of paclitaxel-resistant cervical cancer. Methods . Paclitaxel-resistant Caski cells (Caski/Taxol cells) were …
CDI Exerts Anti-Tumor Effects by Blocking the FoxM1-DNA …
WebMar 7, 2014 · FOXM1 is a transcription factor that transactivates AURKA and other G2/M genes like PLK1, CDK1, and CCNB1 (16) (17) (18). High FOXM1 expression was reported in many cancers including oral... WebJul 11, 2024 · In the current study, we found that DNMT1-mediated FOXO3a promoter hypermethylation leads to downregulation of FOXO3a expression in breast cancer, and FOXO3a suppresses BCSC properties and... royalty\u0027s me
Novel Compound May Block Certain Forms of Aggressive …
WebFeb 27, 2024 · Purpose Few targeted treatment options currently exist for patients with advanced, often recurrent breast cancers, both triple-negative breast cancer (TNBC) and hormone receptor-positive breast cancer. Forkhead box M1 (FOXM1) is an oncogenic transcription factor that drives all cancer hallmarks in all subtypes of breast cancer. We … WebSep 12, 2024 · FOXM1 (forkhead box protein M1) is a critical proliferation-associated transcription factor that is widely spatiotemporally expressed during the cell cycle. It is … WebThe knockdown of FOXM1 also attenuated proliferation and induced G1 arrest in lung cancer cells. Conclusion: CENPU was highly expressed in NSCLC tissues, wherein it promoted lung cancer cell proliferation via the transcription factor, FOXM1, which could be a potential target for therapeutic strategies. royalty\u0027s mc