Circrhobtb3
WebCircRHOBTB3 was downregulated in ovarian cancer tissues and cells. RESULTS: Functionally, circRHOBTB3 overexpression could markedly suppress cell proliferation, metastasis and glycolysis, whereas the opposite results could be observed in the deletion of circRHOBTB3. Additionally, xenograft experiment also identified the above results. WebJun 29, 2024 · CircRHOBTB3 is downregulated in HCC and may suppress cell proliferation by reducing miR-18a production. Introduction Hepatocellular carcinoma (HCC) is a major …
Circrhobtb3
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WebFeb 11, 2024 · circRHOBTB3 is secreted outside of tumor cells and suppresses CRC cells in vitro and in vivo. ( A) Expression of circRHOBTB3 in CRC or normal colonic epithelial … WebJan 13, 2024 · The circRHOBTB3 probe was incubated with streptavidin magnetic beads (Beaver, Suzhou, china) for 2 h to generate probe-coated beads, then incubated with cell lysates, followed by eluted with Trizol (Takara, japan), and qRT-PCR. for miR-654-3p pulled down, about 1 × 10 7 cells were collected, lysed, sonicated, and incubated with …
WebIn a first step, eight circRNAs (circATXN10, circCRIM1, circCSNK1G3, circGUCY1A2, more »... cLPP, circNEAT1, circRHOBTB3, and circSTIL) were identified as differentially expressed via a genome-wide circRNA-based microarray analysis of six PCa samples. Additional bioinformatics and literature data were applied for this selection process. WebJun 2, 2024 · The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p Rising evidences bespeak that circular RNAs are indispensable in regulating cellular biological behaviors and engaging in diseases' occurrence.
WebFor instance, EIF4A3 can induce the expression of circMMP9 and circASAP1, 51, 52 FUS can induce abnormally high expression of circRHOBTB3 and circ_002136 in tumors. 53, 54 Through analysis of the Circular RNA Interactome online database, 55 we found that EIF4A3 and FUS contain binding sites Webing in diseases’ occurrence. CircRHOBTB3 has been reported to participate intimately in the progression of some cancers. Nevertheless, the mechanism by which circRHOBTB3 regulates tumorigenesis in epithelial ovarian cancer (EOC) remains ill-dened. The present study determined the expression pattern and bio-eects of circRHOBTB3 in EOC.
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WebMar 21, 2024 · CircRHOBTB3 interacted with the RNA-binding protein, IGF2BP3, to stabilize its expression in CC cells and is putatively transcriptionally regulated by NR1H4. In conclusion, this novel NR1H4/circRHOBTB3/IGF2BP3 axis may provide new insights into CC pathogenesis. PMID: 36939994 insulated concrete form homes buildersWebDec 1, 2024 · The molecular mechanism of circRHOBTB3 inhibits the proliferation and invasion of epithelial ovarian cancer by serving as the ceRNA of miR-23a-3p Article Full-text available Jun 2024 Yihan Fu... job offer doesn\u0027t allow for two weeks noticeWebJul 27, 2024 · CircRHOBTB3 interacted with the RNA-binding protein, IGF2BP3, to stabilize its expression in CC cells and is putatively transcriptionally regulated by NR1H4. insulated concrete form homes ukWebFeb 11, 2024 · circRHOBTB3 is secreted outside of tumor cells and suppresses CRC cells in vitro and in vivo. (A) Expression of circRHOBTB3 in CRC or normal colonic epithelial … job offer document templateWebOct 9, 2024 · By using microarray analysis and statistical methods, Franz et al. have demonstrated that circRHOBTB3 could act as a diagnostic and prognostic biomarker of clear cell renal cell carcinoma . Besides, it was reported that circFAM13B was decreased in the epithelial ovarian cancer specimens, whereas the specific regulatory mechanism … job offer document for new hiresWebFigure Legend Snippet: circRHOBTB3 promotes PANC-1 cell proliferation by activating autophagy response. a The protein level of p62 and LC3B were determined by western blotting in PANC-1 cells transfected circRHOBTB3 overexpressing vector with or without 3-Methyladenine (3-MA, 2.5 mM, 24 h) treatment. b The mCherry-GFP-LC3B labeled … job offer dublinWebZestimate® Home Value: $329,501. 103 S Brownthrush Cir, Wichita, KS is a single family home that contains 2,848 sq ft and was built in 1994. It contains 4 bedrooms and 3 … insulated concrete form house