WebJul 22, 2024 · Notably, newly identified FGF14 target genes, adenosine deaminase RNA specific B1 (ADARB1), collagen and calcium-binding epidermal growth factor domain-containing protein 1 (CCBE1), α1 chain of collagen XI (COL11A1), and mucin 16 (MUC16) expression was negatively correlated with overall survival when FGF14 was … WebMar 15, 2014 · CCBE1 is capable of increasing the levels of mature, processed VEGFC in vitro, which can rescue ccbe1 loss-of-function phenotypes when overexpressed in vivo. Together, our findings suggest that Ccbe1 activates Vegfc through its processing and release from the ECM in order to regulate lymphangiogenesis and venous sprouting in …
CCBE1 Gene - GeneCards CCBE1 Protein CCBE1 Antibody
WebIn wildtype zebrafish, Ccbe1 was expressed spatially and temporally in the migration routes of lymphatic endothelial cells, but not in lymphatic endothelial cells themselves. Ccbe1 … WebJan 16, 2024 · Collagen and calcium-binding EGF domain-1 (CCBE1) is essential for lymphatic vascular development as it promotes vascular endothelial growth factor C … pottery barn chess
Q6UXH8 - UniProt
WebFeb 19, 2014 · CCBE1 is a 2-domain protein with an N-terminal potential Ca-binding domain with epidermal growth factor–like repeats and a C-terminal domain with collagen-like repeats. Most of the known mutations … WebCCBE1 se está investigando como un posible tratamiento para enfermedades cardiovasculares, como la enfermedad arterial coronaria, la hipertensión arterial y la insuficiencia cardíaca. También se está estudiando su uso en el tratamiento de enfermedades linfáticas, como el linfedema. WebNov 22, 2009 · CCBE1 encodes Collagen and Calcium-Binding EGF domain-1, a secreted protein that has been shown to be required for embryonic lymphangiogenesis in zebrafish. Lymphedema, lymphangiectasias, mental ... tougaloo college health and wellness center